Applied Biochemistry And Biotechnology by RICHARD G. NELSON, MARIE WALSH, JOHN J. SHEEHAN,

By RICHARD G. NELSON, MARIE WALSH, JOHN J. SHEEHAN,

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I noticed recently that you chair the Editorial Board of The Scientist. Our interactions go back to the founding of the Institute for Scientific Information and his bibliographic tools for retrieving scientific data. p65 45 01/21/2002, 4:08 PM 46 Hargittai, Candid Science II by similarity of strings of characters. Garfield had a brilliant idea using the citation linkage as a step in that direction. It gives a sense of connectedness. The scientific literature is a network, and the emergence of citation analysis is putting more of a sense of obligation to report your sources because they will be used in this way.

At that time he was commuting between Stanford and Mexico City, which must have been very exhausting for him. So I’d suggested to Syntex that the mountain should move to Mohammed and that Syntex ought to move its laboratories to Sanford Industrial Park. I had also suggested to start thinking about how to commercialize advances in what we now call biotechnology. So Syntex funded the initiation of an institute. Its early emphasis was nucleotide biochemistry, similar to George Hitchings’s works on some of the modified bases.

22 Hargittai, Candid Science II acknowledged that it was our paper that led his doing that work. Then when we recently celebrated the 50th anniversary of our discovery, he participated in the affair, and we had a chat at that time. He has always expressed himself negatively about Watson and Crick. What was the most important discovery that your work was building upon? It all started with work on pneumonia. It was Fred Griffith in London who had received numerous sputum samples from patients with pneumonia for bacteriologic diagnosis, and he had become interested in the fact that many of the samples from patients contained four or five different pneumococcal types.

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